Microfluidic devices are widely used in biomedical applications owing to their inherent advantages. Microfabrication techniques are common methods for fabricating microfluidic devices, which require specialized equipment. This paper presents a multi-layer construction process for producing microfluidic devices via integrating two accessible fabrication techniques — hydrogel molding, a microfabrication-free method, and electrospinning (ES). The formed microchannels were examined via analyzing micrographs. Preliminary results demonstrate the feasibility of the method and potential for incorporating complex channels and device optimization.

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