Coronary atherosclerotic plaques are frequently focal lesions that have variable rates of progression. Wall shear stresses (WSS) create a number of responses in endothelial cells that can lead to the localization and progression of these lesions, and in vivo coronary segments with low WSS have been found to develop greater plaque progression than segments of higher WSS.
- Bioengineering Division
CFD and VH-IVUS Biomechanical Analysis of Coronary Artery Disease With One Year Follow-Up
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Molony, DS, Timmins, LH, Eshtehardi, P, Samady, H, & Giddens, DP. "CFD and VH-IVUS Biomechanical Analysis of Coronary Artery Disease With One Year Follow-Up." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT03A002. ASME. https://doi.org/10.1115/SBC2013-14313
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