Cartilage is a charged hydrated fibrous tissue exhibiting a high degree of tension-compression nonlinearity (i.e., tissue anisotropy). The effect of tension-compression nonlinearity on solute transport has not been investigated in cartilaginous tissue under dynamic loading conditions. In this study, a new model was developed based on the mechano-electrochemical mixture model [Yao and Gu, 2007, J. Biomech. Model Mechanobiol., 6, pp. 63–72, Lai et al., 1991, J. Biomech. Eng., 113, pp. 245–258], and conewise linear elasticity model [Soltz and Ateshian, 2000, J. Biomech. Eng., 122, pp. 576–586;Curnier et al., 1995, J. Elasticity, 37, pp. 1–38]. The solute desorption in cartilage under unconfined dynamic compression was investigated numerically using this new model. Analyses and results demonstrated that a high degree of tissue tension-compression nonlinearity could enhance the transport of large solutes considerably in the cartilage sample under dynamic unconfined compression, whereas it had little effect on the transport of small solutes (at 5% dynamic strain level). The loading-induced convection is an important mechanism for enhancing the transport of large solutes in the cartilage sample with tension-compression nonlinearity. The dynamic compression also promoted diffusion of large solutes in both tissues with and without tension-compression nonlinearity. These findings provide a new insight into the mechanisms of solute transport in hydrated, fibrous soft tissues.
Skip Nav Destination
e-mail: wgu@miami.edu
Article navigation
June 2007
Technical Papers
Effects of Tension-Compression Nonlinearity on Solute Transport in Charged Hydrated Fibrous Tissues Under Dynamic Unconfined Compression
Chun-Yuh Huang,
Chun-Yuh Huang
Department of Pediatric Dentistry,
Nova Southeastern University
, Ft. Lauderdale, FL
Search for other works by this author on:
Wei Yong Gu
Wei Yong Gu
Tissue Biomechanics Lab, Department of Biomedical Engineering,
e-mail: wgu@miami.edu
University of Miami
, Coral Gables, FL
Search for other works by this author on:
Chun-Yuh Huang
Department of Pediatric Dentistry,
Nova Southeastern University
, Ft. Lauderdale, FL
Wei Yong Gu
Tissue Biomechanics Lab, Department of Biomedical Engineering,
University of Miami
, Coral Gables, FLe-mail: wgu@miami.edu
J Biomech Eng. Jun 2007, 129(3): 423-429 (7 pages)
Published Online: November 6, 2006
Article history
Received:
March 22, 2006
Revised:
November 6, 2006
Citation
Huang, C., and Gu, W. Y. (November 6, 2006). "Effects of Tension-Compression Nonlinearity on Solute Transport in Charged Hydrated Fibrous Tissues Under Dynamic Unconfined Compression." ASME. J Biomech Eng. June 2007; 129(3): 423–429. https://doi.org/10.1115/1.2720920
Download citation file:
Get Email Alerts
Related Articles
Erratum: “Modeling of Neutral Solute Transport in a Dynamically Loaded Porous Permeable Gel: Implications for Articular Cartilage Biosynthesis and Tissue Engineering” [ASME Journal of Biomechanical Engineering, 2003, 125 , pp. 602–614]
J Biomech Eng (August,2004)
The Role of Flow-Independent Viscoelasticity in the Biphasic Tensile and Compressive Responses of Articular Cartilage
J Biomech Eng (October,2001)
Modeling of Neutral Solute Transport in a Dynamically Loaded Porous Permeable Gel: Implications for Articular Cartilage Biosynthesis and Tissue Engineering
J Biomech Eng (October,2003)
A Comparison Between Mechano-Electrochemical and Biphasic Swelling Theories for Soft Hydrated Tissues
J Biomech Eng (February,2005)
Related Proceedings Papers
Related Chapters
Analytical and Numerical Calculation of Hydrogen Desorption Rate During TDS Analysis Using the Kissinger Formula and the McNabb-Foster Model
International Hydrogen Conference (IHC 2012): Hydrogen-Materials Interactions
Effects of Ultrasound Stimulation on Chondrocytes in Three-Dimensional Culture in Relation to the Production of Regenerative Cartilage Tissue
Biomedical Applications of Vibration and Acoustics in Therapy, Bioeffect and Modeling
Introduction
Ultrasonic Methods for Measurement of Small Motion and Deformation of Biological Tissues for Assessment of Viscoelasticity