A convenient method for testing and calibrating surface perfusion sensors has been developed. A phantom tissue model is used to simulate the nondirectional blood flow of tissue perfusion. A computational fluid dynamics (CFD) model was constructed in Fluent® to design the phantom tissue and validate the experimental results. The phantom perfusion system was used with a perfusion sensor based on clearance of thermal energy. A heat flux gage measures the heat flux response of tissue when a thermal event (convective cooling) is applied. The blood perfusion and contact resistance are estimated by a parameter estimation code. From the experimental and analytical results, it was concluded that the probe displayed good measurement repeatability and sensitivity. The experimental perfusion measurements in the tissue were in good agreement with those of the CFD models and demonstrated the value of the phantom tissue system.
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October 2008
Research Papers
A Phantom Tissue System for the Calibration of Perfusion Measurements
Ashvinikumar V. Mudaliar,
Ashvinikumar V. Mudaliar
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
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Brent E. Ellis,
Brent E. Ellis
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
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Patricia L. Ricketts,
Patricia L. Ricketts
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
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Otto I. Lanz,
Otto I. Lanz
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Small Animal Clinical Sciences, Virginia Tech
, Blacksburg, VA 24061-0442
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Elaine P. Scott,
Elaine P. Scott
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
; Department of Engineering, Seattle Pacific University
, Seattle, WA 98119-1957
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Thomas E. Diller
Thomas E. Diller
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
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Ashvinikumar V. Mudaliar
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
Brent E. Ellis
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
Patricia L. Ricketts
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238
Otto I. Lanz
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Small Animal Clinical Sciences, Virginia Tech
, Blacksburg, VA 24061-0442
Elaine P. Scott
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
; Department of Engineering, Seattle Pacific University
, Seattle, WA 98119-1957
Thomas E. Diller
Virginia Tech—Wake Forest University School of Biomedical Engineering and Sciences
; Department of Mechanical Engineering, Virginia Tech
, Blacksburg, VA 24061-0238J Biomech Eng. Oct 2008, 130(5): 051002 (10 pages)
Published Online: July 10, 2008
Article history
Received:
July 25, 2007
Revised:
January 19, 2008
Published:
July 10, 2008
Citation
Mudaliar, A. V., Ellis, B. E., Ricketts, P. L., Lanz, O. I., Scott, E. P., and Diller, T. E. (July 10, 2008). "A Phantom Tissue System for the Calibration of Perfusion Measurements." ASME. J Biomech Eng. October 2008; 130(5): 051002. https://doi.org/10.1115/1.2948417
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