The swirling secondary flow in curved pipes is studied in three-space dimensions using a weakly compressible smoothed particle hydrodynamics (WCSPH) formulation coupled to new nonreflecting outflow boundary conditions. A large eddy simulation (LES) model for turbulence is benchmarked with existing experimental data. After validation of the present model against experimental results for a pipe bend, a detailed numerical study aimed at reproducing experimental flow measurements for a wide range of Reynolds numbers has been performed for different pipe geometries, including U pipe bends, S-shaped pipes, and helically coiled pipes. In all cases, the SPH calculated behavior shows reasonably good agreement with the measurements across and downstream the bend in terms of streamwise velocity profiles and cross-sectional contours. Maximum mean-root-square deviations from the experimentally obtained profiles are always less than %. This combined with the very good matching between the SPH and the experimental cross-sectional contours shows the uprising capabilities of the present scheme for handling engineering applications with streamline curvature, such as flows in bends and manifolds.