In the wear testing of prosthetic joints, the optimal lubricant protein concentration is disputed. The effect of protein concentration of calf serum based lubricant on the wear of ultra-high molecular weight polyethylene against CoCr was studied with a 12-station, circularly translating pin-on-disk device. The wear factor first steeply increased with increasing concentration, reached a peak at 10–20 mg/ml, and then slowly decreased. Below 20 mg/ml, the wear mechanisms were not entirely representative of clinical wear. Above this value, the morphology of the UHMWPE wear surface resembled that of retrieved cups. The results indicated that the concentration should not be below 20 mg/ml. The scope of this recommendation is discussed.
Issue Section:
Technical Papers
1.
Liao
, Y.-S.
, Benya
, P. D.
, and McKellop
, H. A.
, 1999
, “Effect of Protein Lubrication on the Wear Properties of Materials for Prosphetic Joints
,” J. Biomed. Mater. Res.
, 48
, pp. 465
–473
.2.
Saikko
, V.
, and Ahlroos
, T.
, 1999
, “Type of Motion and Lubricant in Wear Simulation of Polyethylene Acetabular Cup
,” J. Eng. Med.
, 213
, pp. 301
–310
.3.
Saikko
, V.
, and Ahlroos
, T.
, 2000
, “Wear Simulation of UHMWPE for Total Hip Replacement With a Multidirectional Motion Pin-on-Disk Device: Effects of Counterface Material, Contact Area, and Lubricant
,” J. Biomed. Mater. Res.
, 49
, pp. 147
–154
.4.
Wang, A., Polineni, V. K., Essner, A., Stark, C., and Dumbleton, J. H., 1998, “Role of Proteins and Hyaluronic Acid in the Lubrication and Wear of UHMWPE Acetabular Cups,” 24th Annual Meeting, Society for Biomaterials, San Diego, Ca., U.S.A.
5.
Yao, J. Q., Laurent, M. P., Gilbertson, L. N., Blanchard, C. R., Crownishield, R. D., and Jacobs, J. J., 2002, “A Comparison of Biological Lubricants to Bovine Calf Serum for Total Joint Wear Testing,” 48th Annual Meeting, Orthopaedic Research Society, Dallas, Tx., U.S.A.
6.
ISO 14242-1 International Standard, 2002, “Implants for Surgery—Wear of Total Hip Joint Prostheses—Part 1: Loading and Displacement Parameters for Wear-Testing Machines and Corresponding Environmental Conditions for Test,” International Organization for Standardization, Geneva, Switzerland.
7.
Bragdon
, C. R.
, O’Connor
, D. O.
, Lowenstein
, J. D.
, Jasty
, M.
, and Syniuta
, W. D.
, 1996
, “The Importance of Multidirectional Motion on the Wear of Polyethylene
,” J. Eng. Med
, 210
, pp. 157
–165
.8.
Wang
, A.
, Polineni
, V. K.
, Essner
, A.
, Sokol
, M.
, Sun
, D. C.
, Stark
, C.
, and Dumbleton
, J. H.
, 1997
, “The Significance of Nonlinear Motion in the Wear Screening of Orthopaedic Implant Materials
,” J. Test. Eval.
, 25
, pp. 239
–245
.9.
Saikko
, V.
, and Calonius
, O.
, 2002
, “Slide Track Analysis of the Relative Motion Between Femoral Head and Acetabular Cup in Walking and in Hip Simulators
,” J. Biomech.
, 35
, pp. 455
–464
.10.
Lowry
, O. H.
, Rosebrough
, N. J.
, Farr
, A.
, and Randall
, R. J.
, 1951
, “Protein Measurement With the Folin Phenol Reagent
,” J. Biol. Chem.
, 193
, pp. 265
–275
.11.
Saikko
, V.
, Ahlroos
, T.
, Calonius
, O.
, and Kera¨nen
, J.
, 2001
, “Wear Simulation of Total Hip Prostheses With Polyethylene Against CoCr, Alumina and Diamond-Like Carbon
,” Biomaterials
, 22
, pp. 1507
–1514
.12.
Atkinson
, J. R.
, Dowson
, D.
, Isaac
, G. H.
, and Wroblewski
, B. M.
, 1985
, “Laboratory Wear Tests and Clinical Observations of the Penetration of Femoral Heads Into Acetabular Cups in Total Replacement Hip Joints III: The Measurement of Internal Volume Changes in Explanted Charnley Sockets After 2–16 Years In Vivo and the Determination of Wear Factors
,” Wear
, 104
, pp. 225
–244
.13.
McKellop
, H. A.
, Campbell
, P.
, Park
, S. H.
, Schmalzried
, T. P.
, Grigoris
, P.
, Amstutz
, H. C.
, and Sarmiento
, A.
, 1995
, “The Origin of Submicron Polyethylene Wear Debris in Total Hip Arthroplasty
,” Clin. Orthop.
, 311
, pp. 3
–20
.14.
Wang
, A.
, Polineni
, V. K.
, Stark
, C.
, and Dumbleton
, J. H.
, 1998
, “Effect of Femoral Head Surface Roughness on the Wear of Ultrahigh Molecular Weight Polyethylene Acetabular Cups
,” J. Arthroplasty
, 13
, pp. 615
–620
.15.
Wang, A., Polineni, V. K., Essner, A., Stark, C., and Dumbleton, J. H., 1999, “Quantitative Analysis of Serum Degradation and Its Effect on the Outcome of Hip Joint Simulator Wear Testing on UHMWPE,” 45th Annual Meeting, Orthopaedic Research Society, Anaheim, Ca., U.S.A.
16.
Saikko
, V.
, Ahlroos
, T.
, and Calonius
, O.
, 2001
, “A Three-Axis Knee Wear Simulator With Ball-on-Flat Contact
,” Wear
, 249
, pp. 310
–315
.17.
Calonius
, O.
, and Saikko
, V.
, 2002
, “Analysis of Polyethylene Particles Produced in Different Wear Conditions In Vitro
,” Clin. Orthop.
, 399
, pp. 219
–230
.Copyright © 2003
by ASME
You do not currently have access to this content.